Instrument description page 11 qtof 2 users guide probe ms1 quadrupole ms ms2 tof ms dynolite point detector mcp detector pusher zspray ion. Many analysis techniques use lcms, which requires a frontend hplc system to provide. Ts5600 users manual technologic systems 5 052209 1 introduction the model ts5600 is a compact, fullfeatured pc compatible single board computer based on the amd elan520 processor. System user guide 5500 series of instruments ruoidv050265a 3 of 6 revision log revision description date a first release of document. It will be important to know what your water hardness is before doing this programming procedure. The food and drug administration fda released a liquid chromatographyhigh resolution mass spectrometry lchrms method for the quantitation of nnitrosodimethylamine ndma in ranitidine drug substance and drug products using the q exactive hybrid quadrupoleorbitrap mass spectrometer. The following limited warranties give you specific legal rights.
I have had experience with their qtof when they were micromass and i loved. Troubleshooting chart after completion of steps 1 4, move the shifting lever to check the shifting. The manufacturer reserves the right to make changes at any time without notice. For the record, we have an ab 5600 and its a great ms, for our application. Electrospray ionization and atm slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. A practical introduction to analysis of intact proteins on the tripletof 5600 system high resolution and high sensitivity for analysis of large biomolecules doug simmons ab sciex, canada the analysis of intact proteins by accurate mass lcms is the method of choice for determining intact mass, protein. System installation requires information from a number of. The operation set of tripletof 5600 ms the tripletof 5600 ms was equipped with a digital picoview esi source new objective, woburn, ma. Before using your ftdx5000, be sure to read and follow the instructions in the before you begin section of this manual. Patient care, professional education and research are carried out at hospitals and. Used only if the input spectra are stored in profile mode i. Power up the data logger and open survey controller software. Finally, locate the meter cable to the rear of the fleck 5600 meter valve, and push the brass tip into the meter dome as shown in figure 27 below.
The ab sciex tripletof 5600 system is designed for the qualitative and. The fiehnlib leco was obtained on a pegasus iv tof instrument using ei ionization from mz 85 to 500. Manual implementation without the documentation of results in the instrument mem. Below are guidelines for ms parameters necessary to build an acquisition method for intact proteins on the tripletof 5600 system. Pn ab sciex product description list price discount net. You can use the procedures to learn how to use the software and the instrument. Identification of potential auxinresponsive small signaling. The following terms and conventions are used in the user s guide. Established in 1911, the university of tennessee health science center aims to improve human health through education, research, clinical care and public service. A acceleration transducer cable and b stimulation cable. This product has been developed to connect your printers anywhere in your network, allowing all network users access to shared printer resources. Q exactive hybrid quadrupoleorbitrap mass spectrometer. It also describes potential hazards and associated warnings for the system and the precautions that should be taken to. Ms1ppm30ppm for ab sciex triple tof 5600, consider setting to 40ppm.
Scientists respond to the ab sciex tripletof 5600 system. The tofwatch is now ready for locating the nerve with the needle electrode. Further processing was performed by an inhouse written program named armone 2. Drager xam 5600 quick user guide switching on the device press and hold the key approx. Acquiring data in manual tune mode in analyst software duration. Locate the center knob on the face of the fleck 5600 meter valve and be sure that the notch in the knob says in serv. Which qtof is best abs triple tof5600 or waters g2s.
The tripletof 5600 system, a hybrid quadrupole timeofflight mass spectrometer, was evaluated to explore the key figures of merit in generating peptide and protein identifications that included. Service manuals for fleck control heads and valves and ro systems provided by abundant flow water systems. Dllab sells and buys preowned, mass specs and delivers spare parts and technical service. Feb 17, 20 vitros 5600 user s manual hi folks, i recently joined a laboratory where vitros 5600 is the analyzer used in clinical chemistry and i am now in the process of getting my self transition to the new analyzer.
Samples were analyzed using an ab sciex triple tof 5600 plus mass spectrometer coupled with the sciex eksigent nanolc system. This manual is a companion to the masslynx nt users guide supplied with the. The user of this product is solely responsible for observing safe boating practices. Peptide solution was loaded into a c18 trap column 5. This is the third lecture in series of lectures on mass spectrometry for pesticides residue analysis. Spectral indices now match between tof tof profile and tof tof peak list data if you converted the same tof tof data to mzml format in both profile. Triple maintenance manual 6975 this manual is divided into sections for ease of viewing. Using an ab sciex tripletof 5600 system to identify and quantitate posttranslationally modified peptides. The entire manual can be downloaded in pdf format by clicking here.
Genotoxic impurity analysis in pharmaceutical products. It applies to the trimble 5600 series total station. The above files contain information about protein identification, protein relative abundance, and ptms identification. Pn ab sciex product description list price discount net price. The tof watch is now ready for locating the nerve with the needle electrode. Dec 14, 2015 this is the third lecture in series of lectures on mass spectrometry for pesticides residue analysis. Operation of this equipment in a residential area is likely to cause harmful interference in which case you will be required to correct the interference, at your own expense.
The q exactive hf system combines a stateoftheart segmented quadrupole for highperformance precurs. Built with versatility in mind, the tripletof technology unleashes sensitivity, speed, and productivity in a single multifaceted platform to help you dig deeper into complex samples. This section contains general safetyrelated information and provides regulatory compliance information. This can be done any time prior to data collection, such as the night before, etc.
Before operating the system, carefully read all of the sections of this guide. Manually index the softener control into the in service position and let water flow into the resin tank. It applies to the trimble 5600series total station. Proteomics analysis of ogalnac glycosylation in human. Hardware limited warranty trimble navigation limited warrants that this. The compact size of the nport 5600 device servers makes them the ideal choice for connecting your rs232 nport 5610168, rs422485 nport 5630168, or. Identify and quantify more proteins, peptides, lipids, glycans and small molecules accurately and in less time with the thermo scientific q exactive hf hybrid quadrupoleorbitrap mass spectrometer. The ut health science center campuses include colleges of dentistry, graduate health sciences, health professions, medicine, nursing and pharmacy.
Labelfree, quantitative full scan filtering workflows in skyline. The tof systems safety guide is installed automatically with the. Q tof 2 users guide micromass uk limited floats road wythenshawe m23 9lz. For electronic valves, please refer to the manual regeneration part of the timer operation section. There are two different fiehn libraries created using either quadrupole or tof mass detectors. This operating manual is the common manual to the ftdx5000, ftdx5000d, and ftdx5000mp. The shimadzu prominence highperformance liquid chromatograph achieves an exceptional level of performance, reliability and great expandability to support diverse applications from ultrafast liquid chromatography to preparative lc, gel permeation chromatography gpc, ion chromatography, and lcms. Just swipe the side or the bottom of the screen and. Mass spectrometric data acquired by triple tof 5600 ms. The file is 75mb each section is word searchable by using ctrlf contents. Before startup a few simple steps must be followed to program the fleck 5600 meter valve. The fiehnlib agilent, was created on a singlequadrupole mass detector operated in fullscan mode with mz ranging from 50 to 650.
Agilent 6200 series tof and 6500 series qtof lcms system. Install the water softener with the inlet, outlet and drain connections made according to manufacturers recommendations and to meet applicable plumbing codes. If you do not know your water hardness, or if you are. Ab sciex triple tof 5600 fully tested and refurbished by spectralab scientific inc. The following terms and conventions are used in the users guide. Chain cn5600 bottom bracket cable guide smsp17 installation of the front derailleur clearance. The recently introduced tripletof 5600 system tripletof, a hybrid triple quadrupole tof platform, is considered the first accurate mass, high resolution system of its kind and operates by means of information dependent acquisition ida with the speed and sensitivity of a tof ms and quantification capabilities similar to a triple quadrupole ms. Quantitative workflows targeting changes in protein. Analytical facility research college of pharmacy uthsc. Thank you for your purchase of a new water softener with fleck 5600sxt meter from. Proteomics analysis of ogalnac glycosylation in human serum.
It uniquely integrates comprehensive, qualitative exploration, rapid profiling, and highresolution quantitation workflows. Q exactive hf hybrid quadrupoleorbitrap mass spectrometer. If the user has requested an acquisition rate of 1 spectrumsecond, each spectrum viewed on the host pc will be the result of summing up to 20,000 individual spectra recorded at the detector. August 2011 7 foreword this guide is for instrument operators who are new to the analyst software. You may have others, which vary from statejurisdiction to statejurisdiction. The mass spectrometry dataset described here consists of 14 files generated from four different analyses in a 5600 triple tof sciex by information. Operation of this equipment in a residential area is likely to cause harmful. Changes or modifications not expressly approved by the. This manual is intended as a guide for service of the valve only. The peptide samples were redissolved in 2% acetonitrile0. Performance characteristics of a new hybrid quadrupole time.
This support is currently limited to tripletof 5600 data. At 3 mhz, it is approximately 10 times faster than our other 386ex based products for only a small additional cost. If the valve came with a separate electronic timer service manual, refer to the timer operation section of the electronic timer service manual. Take on new analytical challenges and extend your research capability with the tripletof 6600 quadrupole timeofflight qtof mass analyzer. Performance characteristics of a new hybrid quadrupole. We have put together these instructions as reference, and to. Qtof 2 users guide micromass uk limited floats road. A practical introduction to analysis of intact proteins on. Navman tracker 5600 installation and operation manual 5 it is the owners sole responsibility to install and use the instrument in a manner that will not cause accidents, personal injury or property damage.
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